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. There are 2 distinctive clades in the virus: clade I (with subclades Ia and Ib) and clade II (with subclades IIa and IIb). In 2022–2023 a global outbreak of mpox was brought on by the clade IIb strain. Secure and highly efficient vaccines are available for 2 viral STIs: hepatitis B and HPV. These vaccines have represented main advancements in